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SGE Isn't For Dummies (I sort of wish it were) 25 Aug 2013 | 07:33 am

Kendall Square used to have the ultimate geek book store, Quantum Books.  No fiction or graphic novels there; it was all technical books.  One could browse every O'Reilly book and many, many others. ...

My biggest contribution to the field of biochemistry 1 Jul 2013 | 08:22 am

LinkedIn has a feature by which one can endorse other people for different fields. Periodically the system prompts me to vote yea-or-nay on a bunch of endorsements, and conversely I get regular update...

An Incomplete Guide to Asking for Help on Your De Novo Genome Project 17 May 2013 | 10:19 pm

I've been thinking about this piece for a while, because I am a frequent presence on SEQAnswers.com and often dive into questions regarding de novo sequence assembly, particularly for small genomes.  ...

What Might Knock Illumina Off Its Perch? 25 Apr 2013 | 08:42 am

The big sequencing platform news this week is Roche's announcement that they are ending their collaborations aimed at developing new sequencing technologies.  A collaboration with DNA Electronics aime...

For What is a 454 Still Great? 5 Apr 2013 | 07:22 am

I've been mulling this item ever since AGBT, but have struggled with the title.  I don't want to sound like I have a grudge against 454 ( truth is I just got some good datasets off this technology), b...

PacBio Back of the Envelope Numbers 4 Mar 2013 | 10:22 am

Back-of-the-envelope calculations can be quite useful, but also quite dangerous.  They are meant to be quick estimates, but can't be taken too seriously.  Still, I try to get them right & deeply regre...

Post AGBT: A Longish Item on Long Sequencing 27 Feb 2013 | 09:27 am

As others have noted, a significant theme at AGBT this year was sequencing at length.  While this year lacked true bombshells, PacBio impressed many with their making single-contig bacterial genome as...

AGBT: Nabsys unveiled 23 Feb 2013 | 05:55 am

In the previous post I described the Nabsys positional sequencer. Yesterday I got o see it running in their hotel suite here at AGBT13. Read more »

AGBT Preview: Nabsys 19 Feb 2013 | 09:00 am

A complaint which seems to be circulating on Twitter and elsewhere is that this year’s AGBT conference on Marco Island next week doesn’t look like it will have any excitement around new platforms.  AG...

Matthew Yuricich: A Pre-Oscar Tribute 17 Feb 2013 | 07:30 am

I'm committing myself this week to an uncommon intensity of posting.  It's AGBT week, and while I'm there I plan to be busy both here and on Twitter.  Genomics has always been the focus of this space,...

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