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Natural infection of Atlantic salmon (Salmo salar L.) with salmonid alphavirus 3 generates numerous viral deletion mutants [ANIMAL: RNA VIRUSES] 16 Aug 2013 | 03:45 am
Salmon pancreas disease virus (SPDV) also referred to as salmonid alphavirus (SAV) is a virus causing pancreas disease in Atlantic salmon (Salmo salar L.) and rainbow trout (Oncorhynchus mykiss). Alth...
Porcine, murine and human sialoadhesin (Sn/Siglec-1/CD169): portals for porcine reproductive and respiratory syndrome virus entry into target cells [A... 16 Aug 2013 | 03:45 am
Porcine sialoadhesin (pSn; a sialic acid-binding lectin) and porcine CD163 (pCD163) are molecules that facilitate infectious entry of porcine reproductive and respiratory syndrome virus (PRRSV) into a...
An interaction between the methyltransferase and RNA dependent RNA polymerase domains of the West Nile virus NS5 protein [ANIMAL: RNA VIRUSES] 16 Aug 2013 | 03:45 am
The flavivirus nonstructural protein 5 (NS5) is a large protein that is structurally conserved among members of the genus, making it an attractive target for antiviral drug development. The protein co...
Targeted mutations in a highly conserved motif of the nsp1{beta} protein impair the interferon antagonizing activity of porcine reproductive and respi... 16 Aug 2013 | 03:45 am
Non-structural protein 1β (nsp1β) of porcine reproductive and respiratory syndrome virus (PRRSV) contains a papain-like cysteine protease (PLPβ) domain and has been identified as the main viral protei...
Highly diversified coronaviruses in neotropical bats [ANIMAL: RNA VIRUSES] 16 Aug 2013 | 03:45 am
Bats host a broad diversity of coronaviruses (CoVs), including close relatives of human pathogens. There is only limited data on neotropical bat CoVs. We analysed faecal, blood and intestine specimens...
Genomic analysis of coxsackieviruses A1, A19, A22, enteroviruses 113 and 104: viruses representing two clades with distinct tropism within enterovirus... 16 Aug 2013 | 03:45 am
Coxsackieviruses (CV) A1, CV-A19 and CV-A22 have historically comprised a distinct phylogenetic clade within Enterovirus (EV) C. Several novel serotypes that are genetically similar to these three vir...
Median infectious dose of human norovirus GII.4 in gnotobiotic pigs is decreased by simvastatin treatment and increased by age [ANIMAL: RNA VIRUSES] 16 Aug 2013 | 03:45 am
Human noroviruses (NoVs), a major cause of viral gastroenteritis, are difficult to study due to the lack of a cell-culture and a small-animal model. Pigs share with humans the types A and H histo-bloo...
Diversity of picornaviruses in rural Bolivia [ANIMAL: RNA VIRUSES] 16 Aug 2013 | 03:45 am
The family Picornaviridae is a large and diverse group of viruses that infect humans and animals. Picornaviruses are among the most common infections of humans and cause a wide spectrum of acute human...
Genetic characterization of a novel picornavirus distantly related to the marine mammal-infecting aquamaviruses in a long-distance migrant bird specie... 16 Aug 2013 | 03:45 am
Despite the continuously growing number of known avian picornaviruses (family Picornaviridae), knowledge of their genetic diversity in wild birds, especially in long-distance migrant species is very l...
Evolutionary dynamics of bovine coronaviruses: natural selection pattern of the spike gene implies adaptive evolution of the strains [ANIMAL: RNA VIRU... 16 Aug 2013 | 03:45 am
Coronaviruses demonstrate great potential for interspecies transmission, including zoonotic outbreaks. Although bovine coronavirus (BCoV) strains are frequently circulating in cattle farms worldwide, ...