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ETS2 mediates tumor suppressor function and MET inhibition in lung adenocarcinoma 13 May 2013 | 10:16 pm
There was a very intriguing paper published online by Clinical Cancer Research on May 9 last week that should be of interest for those involved in lung cancer research. The authors are Mohamed Kabbout...
NKX2-1/TTF-1 drives pulmonary-specific differentiation in lung adenocarcinoma 9 May 2013 | 01:08 am
Snyder et al. recently published an intriguing report in Molecular Cell (21 March 2013) (featured free article) in which they convincingly demonstrate how tumors in which Nkx2-1 was deleted show strik...
CAP releases guidelines for validating whole slide imaging 2 May 2013 | 09:03 am
The College of American Pathologists has released guidelines for validating whole slide imaging. While stating the lack of FDA approval for using WSI for primary diagnosis, the College is acknowledgin...
BRAF mutations in colorectal cancer: mini-review 26 Apr 2013 | 04:58 pm
There has been a recent flurry of papers and reports from ASCO-GI 2013 pushing more molecular testing in colorectal cancer (CRC) and its clinical significance with regard to prognostic and predictive ...
Atomic force microscopy! EMT and idiopathic pulmonary fibrosis 23 Mar 2013 | 06:48 pm
Here is a very intesting article I recently found with some very cool technology: Abstract: Epithelial-mesenchymal transition (EMT) is closely implicated in the pathogenesis of idiopathic pulmonary fi...
Imaging tumors in the future 30 Jan 2013 | 12:37 am
Baohong Yuan and Joshua Rychak have written an interesting review in the February 2013 American Journal of Pathology that outlines emerging techniques based on ultrasound to obtain functional and mole...
Pathologists to Blame for Hindering Acquisition of Cancer Tissue for Genomic Testing? 7 Jan 2013 | 09:26 pm
Medscape recently posted an article that discusses the need for standards for acquiring, preserving and storing cancer tissue, citing a recent Viewpoint article in JAMA by Drs. Laura Goetz, Kelly Beth...
New Device to Check Margins in Breast Cancer Surgery 5 Jan 2013 | 07:53 pm
Just a follow-up to yesterday's post regarding surgical margins in breast cancer. Will this device obviate inking the specimen or the debate about how much margin is "enough"? Quoted from Medscape art...
Controversy: Surgical Margins in Breast Cancer 4 Jan 2013 | 07:00 pm
What is a clear margin in breast-conserving cancer surgery? ASCO Connection (link) hosts a point-counterpoint discussion by two contributors regarding surgical margins in breast cancer that would be o...
Video: Dr. Jack West discusses changing views on molecular testing in NSCLC 4 Jan 2013 | 01:10 am
The Lungevity blog features a video of Dr. Jack West from Swedish Cancer Institute in Seattle discussing his evolving views regarding molecular testing for actionable driver mutations in non-small-cel...
